【摘要】 目的了解宁夏平罗县围产儿出生缺陷发生情况。方法将2003-2007年(未实行出生缺陷综合干预措施,为无干预组)与2008-2009年(期间采取出生缺陷综合干预措施,为干预组)围产儿出生缺陷情况进行比较,评价干预效果。结果平罗县近7年共有围产儿23405例,发生出生缺陷239人,平均发生率102.11/万,其中无干预组发生率108.70/万,干预组发生率79.87/万,发生率显著下降(P<0.05);综合干预后危险因素暴露比例较干预前的29.73%减少明显(P<0.05)。结论采取综合干预措施可以降低严重出生缺陷的发生率,减少危险因素暴露比例。更多还原

【Abstract】 Objective To investigate the prevalence of birth defects in Pingluo district in Ningxia and its risk factors,in order to evaluate the effects of comprehensive intervention in the recent 2 years.Methods The data of birth defects between 2003-2007(control group) and 2008-2009(intervention group) were compared,and the results of comprehensive intervention were analyzed.Results There were 239 birth defects in 23405 neonates in the past 7 years;the prevalence of birth defects was 1.10% in control group and 0.80% in intervention group.The exposure ratios of risk factors,and prevalence of birth defects decreased significantly,and sequence of birth defects changed significantly after intervention(P < 0.05).Conclusion Comprehensive intervention can reduce the rates of the severe birth defects,decrease the exposure ratios of risk factors.更多还原