【摘要】 目的探讨酮症倾向糖尿病(DKA)患者的分型及治疗。方法将70例酮症倾向的糖尿病(KPD)患者,根据体重指数分为超重与肥胖组52例与体重正常组18例,比较两组发病年龄、性别、病程、糖化血红蛋白、生化指标、治疗方式及胰岛功能。结果两组在发病年龄、病程等方面无统计学意义(P>0.05);超重及肥胖组胰岛储备功能好于体重正常组,有统计学意义(P<0.05),但胰岛素抵抗指数(Homa-IR)两组无统计学意义(P>0.05)。结论与体重正常组比较,超重及肥胖组尚保留一定的胰岛素分泌功能,更倾向于2型糖尿病的诊断。在胰岛素短期治疗后,可以改用口服降糖药物治疗。更多还原

【Abstract】 Objective To learn the clinical characteristics and therapy of ketosis-prone diabetes.Methods The patients with KPD were divided into over body weight group and normal body weight group.Clinical characteristics,including age,sex,and mode of presentation,marker of chemical examination,HbA1c therapy mode,and islet beta-cell functional were compared between two groups.Results There were no difference in age,process of disease between two groups(P > 0.05).But the better islet beta cell function al of over weight group than that in normal body weight group(P < 0.05),and there was no difference in insulin resistance between the two groups(P > 0.05).Conclusion patients with ketosis-prone diabetes with the over weight group are more likely to have features associated with type 2 diabetes and better beta-cell functional;the treatment could turn back to oral agents after insulin treatment in a short time更多还原