【摘要】 目的:探索溶血磷脂酸的表达水平与卵巢肿瘤的临床和生物学行为之间是否存在一定的关系。方法:应用生物化学法检测48例卵巢上皮癌、30例卵巢良性上皮肿瘤患者和10例健康妇女的血浆LPA水平。结果:卵巢上皮癌患者血浆LPA水平明显高于卵巢良性上皮肿瘤患者及健康妇女(P<0.01),卵巢良性上皮肿瘤患者与健康妇女血浆LPA水平差异无统计学意义。结论:LPA在卵巢上皮癌患者中呈高表达,具有潜在的早期诊断价值。更多还原

【Abstract】 Objective:To search for the relationships among the plasma level of LPA,theclinical and biological behavior of epithelial ovarian tumor.Methods: The level of plasma LPA was detected bv LPA biochemistry kit in patients with malignant epithelial ovarian carcinoma(48 cases)and benign epithelial ovarian tumor(30 cases),and healthy volunteers(30 cases).Results: Plasma LPA level in patients with epithelial ovarian carcinoma was significantjy higher than that in the patients with benign epithelial ovarian tumor(P<0.05) and in healthy volunteers(P<0.01),while there was not a distinctive difference in plasma LPA leve J between the patients with benign epithelial ovarian tumot and healthy volunteers.Conclusions: Plasma LPA level in patients with epithelial ovarian carcinoma was significantly increased.LPA may play an important role in the carcinogenesis of epithelial ovarian carcinoma.Plasma,LPA level might represent a potential biomarker for diagnosis of ovarian cancer.更多还原