【摘要】 目的:研究血浆白蛋白水平与老年慢性心力衰竭(CHF)患者预后的关系。方法:选择确诊为CHF的老年患者128例,按照血浆白蛋白水平分为4组:白蛋白低水平组、白蛋白较低水平组、白蛋白正常低限组和白蛋白高水平组。采用COX回归分析血白蛋白等因素对生存时间的影响。结果:白蛋白高水平组是预后的保护性因素,白蛋白低水平组及年龄是预后的危险因素,白蛋白较低水平组及白蛋白正常低限组对预后无明显影响(P>0.05)。与存活患者相比,死亡患者高龄,合并心房纤颤、贫血和肾功能衰竭的比例高。结论:血清白蛋白水平与CHF老年患者病情严重程度和病死率有密切关系,低蛋白血症常提示预后不良,输注人血白蛋白制品对改善CHF老年患者的短期预后作用不明显。更多还原

【Abstract】 Objective:To study the relationships between serum albumin and prognosis of elderly patients with chronic heart failure(CHF).Methods:One hundred and twenty-eight elderly patients diagnosed with chronic heart failure were divided into low level of albumin group,relatively low level of albumin group,normal level of albumin group and high level of albumin group according to the level of serum albumin.The effect of serum albumin on survival time was analyzed by COX regression.Results:High level of albumin is a protective factor for prognosis,low level of albumin and age were the risk factors for prognosis,relatively low level of albumin and normal level of albumin had no significant effect on prognosis(P>0.05).Compared with those of survivors,nonsurvivors were older and had a higher proportion of complicating atrial fibrillation,kidney failure and anemia.Conclusions:Level of albumin is closely associated with the severity and mortality of elderly patients with CHF.Hypoproteinemia indicates unfavourable prognosis.Infusion of human blood albumin had no significant improvement in short-term prognosis in elderly patients with CHF.更多还原