【摘要】 目的:探讨灰阶(GS)和能量多普勒(PD)超声在类风湿性关节炎(RA)活动度评估中的价值。方法:测定40例RA患者的包括28个关节的疾病活动度评分(DAS28)、红细胞沉降率(ESR)、C-反应蛋白(CRP)。使用GS与PD对双侧腕关节、第2至第5掌指关节和近端指间关节共18个关节进行滑膜炎评分。结果:与体格检查相比,超声检出滑膜炎的关节数更多。灰阶超声阳性关节计数(GSJC)、灰阶超声积分(GSJS)、能量多普勒积分(PDJS)与DAS28正相关,能量多普勒阳性关节计数(PDJC)与DAS28无显著性相关;PDJC、PDJS、GSJS与ESR、CRP正相关,GSJC与ESR、CRP与无显著性相关。结论:超声具有评估RA活动度的潜在价值。更多还原

【Abstract】 Objective:To score the synovitis in patients with rheumatoid arthritis (RA) using grey scale (GS) and power Doppler (PD) ultrasonography (US),and explore the potential value of the two methods for assessment of disease activity. Methods:The DAS28,ESR and CRP of 40 RA patients were recorded. A total of 18 joints,including bilateral wrist,the second through fifth metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints,were examined using GSUS and PDUS measures to derive US scores for each patient. Results:US detected significantly more joints with synovitis than clinical examination did. The GS joint count (GSJC),GS joint score (GSJS) and the PD joint score (PDJS) were significantly correlated with DAS28. The PD joint count (PDJC),PDJS and the GSJS were significantly correlated with ESR and CRP. We did not find significant correlations between the PDJC and DAS28. Similarly,GSJC did not correlate with ESR and CRP. Conclusion:Sonography has the potential to evaluate disease activity in RA patients.更多还原