【摘要】 目的探讨多次体外冲击波碎石(ESWL)对肾脏的影响。方法对1997年3月~1998年10月间多次(平均7次,每次冲击波次数1 500~3 000次)ESWL的14例肾结石患者进行10年的随访。结果血压、血肌酐(Cr)、尿素氮(BUN)、尿γ谷氨酰转移酶(γ-GT)和尿β2微球蛋白(β2-MG)的平均值均在正常范围。治疗侧肾脏的肾小球滤过率(GFR)无明显变化。随访10年,14例患者未发现有肾脏萎缩现象。结论体外冲击波碎石是治疗肾结石的有效方法,多次碎石对肾脏造成的损害可逐渐恢复,但随着经皮肾镜技术的发展,对复杂肾结石的治疗应综合考虑治疗方式。更多还原

【Abstract】 Objective To evaluate the influence of repeated extracorporeal shock wave lithotripsy(ESWL) on the involved kidneys.Methods 14 cases of renal stones were analyzed retrospectively,which underwent repeated ESWL(mean 7 times) from March 1997 to October 1998.Results The average values of blood pressure,Cr,BUN,γ-urineglutamyl transpeptidase(γ-GT),and β2-microglobulin(β2-MG) were within normal ranges.Glomerular infiltration rate(GFR) had not markedly changed.Conclusions ESWL is an effective way to cure renal stones.Its harmful effects on renal parenchyma and function may recover spontaneously.With development of percutaneous nephrolithotomy(PCNL),therapeutic methods for complicated cases should be considered carefully.更多还原