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良性前列腺增生症合并糖尿病患者尿动力学改变及其临床意义

Clinic significance of urodynamic analysis in patients with benign prostatic hyperplasia complicated with diabetes mellitus

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【作者】 李先承宋希双张志伟李秀男陈峰李晓昕

【Author】 LI Xian-cheng,SONG Xi-shuang,ZHANG Zhi-wei,LI Xiu-nan,CHEN Feng,LI Xiao-xin(Department of Urology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China)

【机构】 大连医科大学附属第一医院泌尿外科

【摘要】 目的通过尿动力学检查对前列腺增生症(BPH)合并糖尿病患者的下尿路症状评估,分析尿动力学的表现,对该类型患者作出合理的治疗与处理。方法 99例行TURP治疗的BPH患者,分成2组,BPH伴糖尿病患者32例(糖尿病组);单纯BPH患者67例(对照组)。对两组的尿动力学结果进行对比分析。结果对糖尿病组和对照组的膀胱感觉减退、顺应性增加、不稳定膀胱的发病率进行比较,P值分别是0.044、0.046、0.130。对糖尿病组和对照组的FDV、MCC、BC、PVR、Pmax、Qmax检测指标进行比较,P值分别是0.004、0.441、0.925、0.005、0.053、0.002。结论前列腺增生症合并糖尿病患者在膀胱感觉减退,膀胱顺应性增加,初始尿意容量、残余尿增加,最大尿流率降低方面与单纯前列腺增生症患者相比,均具有显著性差异(P<0.05)。可见糖尿病加重了前列腺增生症患者的膀胱功能障碍,尿动力学检查对于BPH合并糖尿病患者具有重要的临床参考价值。

【Abstract】 Objective To investigate the effect and significance of diabetesmellitus(DM)on the detrusor of benign prostatic hyperplasia(BPH) with urodynamic studies.Methods A total of 99 BPH patients treated with TURP were divided into two groups.32 patients with BPH complicated with DM were recognized as experimental group,and 67 patients with simple BPH were recognized as control group.The results of urodynamic analysis between the two groups were compared.Results The ratio of patients with decreased bladder sensation or high compliance bladder was higher in the research group than in the control group(P<0.05),The FDV and PVR were higher but the Qmax was lower in the research group than in the control group(P<0.05).The rate of DI,Pmax,MCC and BC had no significant difference between the two groups.Conclusions The impaired detrusor function is more severe in BPH complicated with DM than in simple BPH.Urodynamic examination is significant to decide which patient are suitable to be operated and to predict the prognosis of the operation.

  • 【文献出处】 现代泌尿外科杂志 ,Journal of Modern Urology , 编辑部邮箱 ,2010年06期
  • 【分类号】R697.32
  • 【被引频次】10
  • 【下载频次】157
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