【摘要】 目的对多个牙先天缺失患者进行临床检查和系谱分析,总结先天缺牙的遗传方式和临床特点。方法收集先天缺牙病例,对符合要求的患者及家系成员进行口腔检查,摄曲面断层片;绘系谱图;进行总结分类。结果共收到10个先天缺牙家系;多数牙先天缺失有家族性的,也有散发的,患者常伴有余留牙的形态异常。结论先天缺牙家系多为常染色体显性遗传伴不完全外显;遗传表现包括缺牙牙位、牙冠形态等;先天缺牙严重影响患者的口腔及身心健康。更多还原

【Abstract】 Ojective To explore clinical characteristics and condition of congenital oligodontia.Methods The patients of no-syndromic oligodontia were selected and examined with oral cavity and system,then were taken by panoramic radiograph and analyzed statistically.Results The patients had many kinds of clinical manifestation.Some of them had family history,while others did not have.At the same time,some agenesis patients had obvious abnormity conformation of their teeth.The condition can be inherited as an autosomedominant mainly and a ancestry with autosome-recessive.Conclusion The congenital teeth agenesis maily is autosomal dominant inheritant disease.The inheritant appearances include the deleted tooth number and crown shape.Congenital teeth agenesis influences oral health and occlusion.更多还原