【摘要】 目的探讨肌钙蛋白Ι(cTnI)、B型钠尿肽(BNP)和超敏C反应蛋白(hsCRP)在2型糖尿病(T2DM)合并急性心肌梗死(AMI)患者早期诊断中的价值。方法采集32例T2DM合并AMI(T2DM)患者、40例非DM的AMI(NDM)患者血样本,比较cTnI、BNP和hsCRP水平的变化,并对累及梗死部位进行比较。结果 T2DM组的BNP和hsCRP水平高于NDM组,差异有统计学意义(P<0.01),两组cTnI水平的差异无统计学意义(P>0.05);联合检测阳性率高于单项测定值;冠状动脉造影提示T2DM组冠脉多部位病变发生率高(P<0.05)。结论 cTnI、BNP和hsCRP联合检测对T2DM合并AMI患者的早期诊断具有重要价值。更多还原

【Abstract】 Objective To investigate the early diagnosis value of type 2 diabetes mellitus patients with acute myocardial infarction by detecting troponin(cTnI),B-type natriuretic peptide(BNP)and high sensitive C-reactive protein(hsCRP).Methods 32 cases of type 2 diabetes mellitus with acute myocardial infarction and 40 cases of non-diabetes acute myocardial infarction were collected for a comparative analysis of concentration and site of infarction identified by coronary arteriongraphy.Results In comparison to non-diabetic group,diabetic group demonstrated significantly elevated levels of BNP and hsCRP(P<0.01),but there was no significant difference with cTnI(P>0.05).Combination of cTnI,BNP and hsCRP measurements maybe highly effective for diagnosis.Furthermore,coronary arteriongraphy indicated that pathological changes were more complicated in diabetic group(P<0.05).Conclusion The concentration of cTnI,BNP and hsCRP may provide an important evidence in the early diagnosis of type 2 diabetes mellitus patients with acute myocardial infarction.更多还原