【摘要】 以辛弗林的吸附量、解吸率和所得粉末中辛弗林的含量为指标,从选用的6种大孔吸附树脂中筛选出较好的AB-8树脂。通过静态和动态实验,对辛弗林在AB-8树脂上吸附和解吸的条件进行优化,并考察其吸附等温线、吸附和解吸性能。结果表明,在环境温度约25℃下,使用AB-8树脂纯化辛弗林的较优工艺参数为:上柱液pH值7～8,流速2BV/h,溶液处理量3BV,洗脱剂为20%乙醇,洗脱速度1BV/h,收集洗脱液3BV。按此工艺条件,辛弗林的解吸率为87.2%,3BV洗脱液浓缩干燥后,所得粉末中辛弗林含量为56.6%。更多还原

【Abstract】 Macroporous resin was selected for the separation of synephrine with adsorption capacity,elution ratio and the content of synephrine in the powder obtained as criteria.Experimental results showed that macroporous resin AB-8 was more suitable for the separation and purification of synephrine among 6 kinds of resins selected.Optimal conditions for adsorption and elution of synephrine were performed with static and dynamic experiments.Adsorption isothermal curve,adsorption and elution properties of resin AB-8 were also investigated.The result showed that the optimum technology parameters under room temperature at about 25℃:the pH value of solution treated was 7 to 8,flow rate 2BV/h,the volume of solution treated was 3BV,synephrine adsorbed could be desorbed by 20%alcohol at flow rate 1BV/h,and collected 3BV eluent.The desorption ratio of synephrine was 87.2% according the adsorption and desorption conditions above,the content of synephrine in powder obtained from 3BV eluent through concentration and dry was 56.6%.更多还原