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老年甲状腺结节性病变96例临床分析

Clinical Analysis of the Elderly Nodular Thyroid Disease

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【作者】 杨宇红张龙富刘溯曹东华孙熙融

【Author】 YANG Yuhong ZHANG Longfu LIU Su CAO Donghua SUN Xiron Department of Geriatrics,Changning District Central Hospital,Shanghai 200336,China

【机构】 上海市长宁区中心医院老年科

【摘要】 目的:分析老年人甲状腺结节性病变的特点。方法:回顾分析96例因非甲状腺疾病就诊的住院老年患者的临床资料,患者于入院后次日清晨抽空腹静脉血测游离三碘甲状腺原氨酸(free triiodothyronine,FT3)、游离甲状腺素(free thyroxine,FT4)及促甲状腺素(thyroid-stimulating hormone,TSH)等指标,行甲状腺B超检查,并对手术患者进行随访。结果:(1)老年人甲状腺结节的患病率67.71%,其中男女患病率有显著差异;(2)在甲状腺结节患者中,慢性支气管炎及恶性肿瘤的患病率明显增加(P<0.05)。(3)TSH越高,骨密度(bone mineral density,BMP)越低,两者呈负相关。(4)11例甲状腺结节患者进行手术治疗,病理诊断为:甲状腺乳头状癌1例,腺瘤3例,结节性甲状腺肿7例,9例术后甲状腺过氧化物酶抗体(thyroid per-oxidase antibody,TPOAb)升高,均需长期应用左旋甲状腺素。结论:老年人甲状腺结节的患病率较高,女性患病率更高;甲状腺结节患者中慢性支气管炎及恶性肿瘤的患病率明显增加;TSH与骨密度呈负相关;老年人甲状腺结节绝大多数为良性,应以内科随访及治疗为主,手术则需谨慎。

【Abstract】 Objective:To analysis the elderly nodular thyroid disease patterns.Methods: 96 cases of hospitalized elderly patients for non-thyroid disease treatment.The next morning after admission,free triiodothyronin(FT3),free thyroxine(FT4),thyroid-stimulating hormone(TSH) and other indicators with fasting blood were measured.All case test thyroid with high-resolution B ultrasonicline.Surgical patients were followed-up.Results:(1) The prevalence rate of thyroid nodules for the elderly was 67.71%,of which the prevalence rate for men and women were significantly different;(2)The incidence of thyroid nodules have increased significantly in chronic bronchitis and malignancy.(3)TSH and bone mineral density(BMP) was negative related.(4)Eleven cases of thyroid nodules for surgical treatment,One case was thyroid cancer,pathologically confirmed as a mammilla carcinoma,Three cases were adenoma,Seven cases were nodular.The level of thyroid peroxidase antibody in nine cases(TPO) increased,required alternative long-term L-T4.Conclusions: The prevalence rate of thyroid nodules for elderly is high,and the number of women is higher incidence.Thyroid nodules in patients with chronic bronchial Inflammation and the prevalence rate of malignancy increased significantly.The higher of TSH,the lower of BMP.The majority of the elderly for benign thyroid nodules should be based medicine and follow-up,and the surgery should be cautious.

  • 【文献出处】 中国临床医学 ,Chinese Journal of Clinical Medicine , 编辑部邮箱 ,2010年01期
  • 【分类号】R581
  • 【被引频次】7
  • 【下载频次】131
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