【摘要】 目的:对北京和上海两城市抽样人群的脑卒中发病率及危险因素暴露情况进行比较和分析,为脑卒中预防提供参考。方法:在北京市石景山区和上海市奉贤区以整群抽样方法抽取人群中年龄≥40岁者为目标人群(北京2910名,上海5244名)。设计统一的调查表格,对目标人群进行基线调查,并进行脑循环动力学检测,此后随访脑卒中的发病情况。比较和分析两城市脑卒中发病率、危险因素及脑循环动力学综合积分的差异。结果:北京市和上海市高血压病、心脏病、糖尿病、血脂异常、脑卒中家族史、肥胖、吸烟、饮酒因素的暴露率分别为34.64%和21.09%、23.16%和5.53%、10.79%和2.38%、23.02%和2.59%、28.63%和7.70%、26.74%和4.27%、36.8%和33.6%、36.9%和18.5%,地区间各因素暴露率的差异有统计学意义(P<0.01)。脑卒中发病密度分别为6.29‰和2.51‰。男女组间各危险因素暴露率、脑循环动力学积分值及脑卒中发病率差异均有统计学意义(P<0.01)。结论:北京市高血压、心脏病、糖尿病、血脂异常等脑卒中危险因素暴露率、脑循环动力学损害及脑卒中发病率均显著高于上海市。脑循环动力学损害可能是影响脑卒中发病的重要因素。更多还原

【Abstract】 To compare and analyze the morbidity of stroke and exposure of risk facts between the two sampling groups from Beijing and Shanghai,to provide the reference for stroke prevention.Methods:To pick out target groups above 40 years old,from Shijingshan district of Beijing and Fengxian district of Shanghai, which involved 2910 from Beijing and 5244 form Shanghai,by means of group sampling.To do baseline survey by uniformly designed form,cerebrovascular hemodynamic detection in the target groups,and then the target patients for stroke were followed-up every year.The difference of mortality,risk factors of stroke and cerebrovascular hemodynamics scores were compared and analyzed between the two cities.Results:The exposure rates of hypertension,cardiopathy,diabetes,lipid abnormal,family history of stroke,obesity,smoke, drink of the two cities are separately 34.64%vs 21.09%,23.16%vs 5.53%,10.79%vs 2.38%,23.02%vs 2.59%, 28.63%vs 7.70%,26.74%vs 4.27%,36.8%vs 33.6%,36.9%vs 18.5%(P<0.01).The incidence densities of stroke are 6.29‰and 2.51‰.The differences between the groups of man and women,including exposure of risk factors,cerebrovascular hemodynamic detection scores and incidence rate of stroke were remarkable(P<0.01). Conclusion:The exposure rate of hypertension,heart disease,diabetes,abnormality of lipids and cerebrovascular hemodynamics compound scores,and incidence of stroke of Beijing were distinctly higher than that of Shanghai, the damage of cerebrovascular hemodynamics maybe the key factors that cause stroke.更多还原