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脑静脉窦血栓形成的临床与影像学特点
Clinical and imaging features of cerebral venous sinus thrombosis
【摘要】 目的探讨脑静脉窦血栓形成(CVST)的临床与影像学特点。方法回顾性分析35例CVST患者的临床资料。结果本组29例(82.9%)为中青年患者。临床表现头痛32例(91.4%),视物模糊13例(37.1%),癫疒间发作8例(22.9%)。腰穿脑脊液检查26例,压力增高25例(96.1%)。CT显示脑静脉窦异常3例(17.6%);MRI显示脑静脉窦异常12例(50%),为T1、T2高信号;MRI+磁共振静脉血管成像(MRV)显示脑静脉窦异常21例(100%);DSA显示脑静脉窦异常25例(92.6%)。本组均予以抗凝、脱水及血管内介入治疗,痊愈11例,好转23例。结论 CVST的临床特点是中青年人发生率高,以头痛等颅高压症状为主要表现。CT的诊断率较低,MRI+MRV及DSA的确诊率高,能显示闭塞的静脉窦及其血栓形成。CVST患者应及时予以抗凝治疗,若条件允许可行介入治疗。
【Abstract】 Objective To explore the clinical and imaging features of cerebral venous sinus thrombosis(CVST).Methods The clinical datas of 35 patients with CVST were retrospectively analyzed.Results There were 29(82.9%) middle-aged or young patients.The clinical manifestation showed headache in 32 cases(91.4%),blurred sight in 13 cases(37.1%),epilepsy in 8 cases(22.9%).There were 25 patients(96.1%) with cerebrospinal fluid(CSF) pressure increased in 26 patients with lumber puncture CSF examination.CT showed abnormal cerebral venous sinus in 3 patients(17.6%);MRI showed abnormal cerebral venous sinus in 12 patients(50%) with high T1 and T2 signal;MRI+MRV showed abnormal cerebral venous sinus in 21 patients(100%);DSA showed abnormal cerebral venous sinus in 25 patients(92.6%).11 patients recovered and 23 patients improved after treated with anticoagulation,dehydration and endovascular intervention.Conclusions The clinical feature of CVST is that the incidence rate is high in middle-aged and young patients and intracranial hypertension such as headache is the chief manifestation.The diagnostic rate of CT is low,while which of MRI+MRV or DSA is high.The occlusive venous sinus and thrombosis can be showed by them.The patients with CVST should be treated with anticoagulation in time,and they can accept interventional therapies if having proper condition.
【Key words】 cerebral venous sinus,thrombosis; clinical feature; imaging;
- 【文献出处】 临床神经病学杂志 ,Journal of Clinical Neurology , 编辑部邮箱 ,2010年02期
- 【分类号】R743.32
- 【被引频次】14
- 【下载频次】272