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耐多种药物寻常狼疮

Lupus vulgaris infected with multi-drug resistant tuberculosis

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【作者】 莫衍石潘鹏王立阳杨应周

【Author】 MO Yan-shi, PAN Peng, WANG Li-yang, YANG Ying-zhou (Department of Dermatology and Venereology, Shenzhen Chronic Disease Control Center, Shenzhen 518020, China)

【机构】 深圳市慢性病防治中心皮肤性病科深圳市慢性病防治中心肺科

【摘要】 报告1例耐多种药物寻常狼疮。患者男,41岁。肛周出现红斑、溃疡2年余。5年前曾患肺结核。皮损组织病理检查示真皮浅层可见结核结节,诊断为寻常狼疮,经规则抗结核治疗无效。组织人型结核分枝杆菌培养阳性。药敏试验对异烟肼、利福平等4种抗结核药耐药。提示为耐多种药物寻常狼疮。

【Abstract】 A 41-year-old man has been diagnosed as lupus vulgaris. Perianal erythema and ulcers have lasted for about 2 years while he began to have pulmonary tuberculosis 5 years ago. Histopathological detection of lesion showed that tuberculous tubercle presented in shallow dermis. Lowenstein-Jensen culture with tissue fluid from lesion was positive for bacillus tubercu-losis typus humanus, Regular anti-TB treatment was not effective, which is identified as multidrug-resistant(MDR), including isoniazid, rifampicin, ethambutol and rifapentine.

【关键词】 寻常狼疮耐药,多种药物
【Key words】 lupus vulgarisresistancemulti-drug
  • 【文献出处】 临床皮肤科杂志 ,Journal of Clinical Dermatology , 编辑部邮箱 ,2010年02期
  • 【分类号】R529.4
  • 【被引频次】1
  • 【下载频次】20
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