【摘要】 报告1例泛发性疣状血管瘤并发智力低下。患者女,16岁。面部、躯干和四肢瘀斑、毛细血管扩张16年,疣状增生8年,皮损表现为面部和胸背部紫红色斑疹、斑片和毛细血管扩张,双手、臀部及双下肢见特征性铠甲样外观,周同有多发卫星灶。组织病理检查示表皮角化过度,棘层不规则增生,呈乳头瘤样改变,真皮乳头层及中深层、皮下组织均可见增生和扩张的血管腔,腔中充满红细胞。简易智力状态检查(MMSE)评分为11分。头颅磁共振成像示:①大脑发育不良(胼胝体发育不良、脑白质发育不良、透明隔囊肿);②左额顶部颅板下结节异常信号影,结合病史考虑颜面部血管瘤病。临床诊断:泛发性疣状血管瘤并发智力低下。更多还原

【Abstract】 A case of generalized verrucous haemangioma with mental retardation is reported. A 16-year-old female presented with ecchymosis and telangiectasis all over the body for 16 years, verrucous hyperplasia for 8 years. Physical examination showed purple red macules and telangiectasis on the face and trunk, verrucous hyperplasia characterized as an armour appearance on the dorsum of hands, buttock and lower limbs. Histopathological examination showed hyperkeratosis and papillomatosis, dilated blood-filled spaces in dermis and subcutis. Mini-Mental State Examination score was 11. MRI revealed cerebral hypogenesis, including callosum, white matter of brain, and cyst of septum pellucidum. The diagnosis is generalized verrucous haemangioma with mental retardation.更多还原