【摘要】 目的分析全麻患者术中知晓发生情况,探讨术中知晓的预防措施。方法根据手术中麻醉维持方法的不同,539例全麻下行择期外科手术患者分为三组:A组278例,采用分次静注芬太尼、咪唑安定、维库溴铵维持麻醉;B组119例,术中以微泵持续静注丙泊酚2～4 mg.kg-1.h-1,间断静注芬太尼、咪唑安定、维库溴铵;C组142例,在A组静脉复合全麻基础上,持续吸入0.5%～2.5%异氟醚。分析术中知晓发生情况,计算术中知晓发生率。结果 539例全麻患者麻醉手术期间发生术中知晓28例,发生率为5.20%。其中,A组发生术中知晓19例(6.84%),明显高于B组的5例(4.20%)和C组的4例(2.82%)(P<0.05)。结论用微泵持续静注适量丙泊酚的全凭静脉复合全麻或采用静-吸复合麻醉,可有效降低术中知晓的发生率。更多还原

【Abstract】 Objective To analyze the awareness during operation in patients under general anesthesia.Methods A total of 539 patients underwent operation under general anesthesia was divided into three groups of A(using total intravenous anesthesia with intermitant injection of fentanyl,midazolam and vecuronium,278 cases),B(group A+propofol 2-4 mg·kg-1·h-1 pumping,119 cases) and C(group A+0.5%-2.5% isoflurane inhalation,142 cases).The awareness during operation was recorded.Results A total of 28 cases complained awareness during operation with an incidence rate of 5.20%,which was 6.84%(19/278) in group A,4.20%(5/119) in group B and 2.82%(4/142) in group C.The incidence rate of awareness during operation was significantly higher in group A than that in group B or group C(P<0.05).Conclusion Total intravenous anesthesia with propofol pumping or conbined with inhalation anesthesia may effectively reduce the awareness during operation in patients under general anesthesia.更多还原