【摘要】 目的:探讨核素肾动态显像法测定肾小球滤过率（GFR）在老年肾癌患者中的临床应用价值。方法:回顾性分析30例老年肾癌患者术前及术后1个月应用⁹⁹锝-二乙三胺五乙酸(⁹⁹TC-DTPA)肾动态显像法测定GFR的结果,对健侧肾及术侧残肾进行手术前后的比较,观察其代偿性变化。结果:肾根治性切除组术后健侧肾GFR为（57.6±11.8）ml/min,较术前健侧肾（41.2±7.4）ml/min增加39.8%,但与术前双肾GFR（74.9±12.8）ml/min比较则下降了23.1%。肾部分切除组术侧残肾GFR为（27.8±4.8）ml/min,较术前（36.5±6.4）ml/min减少23.9%,健侧肾GFR手术前后比较差异无统计学意义。结论:采用核素肾动态显像法测定GFR在评估老年肾癌患者分肾功能、选择手术方式及监测术后肾功能方面有重要临床价值。更多还原

【Abstract】 Objective:To explore the clinical value of renal dynamic scintigraphy for evaluating renal function of elder renal cell carcinoma patients.Methods:⁹⁹TC- DTPA are performed for determining and investigating GFR before and after operation in 30 cases of elder renal cell carcinoma patients.Results:The uninjured side kidney GFR of radicalnephrectomy cases increased by 39.8%compared with that before operation（41.2±7.4）ml/min vs（57.6±11.8）ml/min,decreased by 23.1%compared with total GFR before operation（74.9±12.8）ml/min.The residual kidney GFR of operation side decreased by 23.9%compared with that before operation（36.5±6.4）ml/min vs （27.8±4.8）ml/min.The GFR change of uninjured side was unobvious before and after operation.Conclusions:Renal dynamic scintigraghy for evaluating renal function has an important clinical value for elder renal cell carcinoma patients to determine modus operandi and monitore renal function after operation.更多还原