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汉、维吾尔族神经症患者视觉事件相关电位P300对比研究

Comparison of the visual event-related potential P300 between the Han and the Uighur patients with neurosis

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【作者】 万俊玲张薇

【Author】 WAN Jun-ling,ZHANG Wei. Department of Clinical Psychology,The First Affiliated Hospital of Xin-jiang Medical Unniversity,Wulumuqi 830054,China

【机构】 新疆医科大学第一附属医院临床心理科

【摘要】 目的:探讨汉族与维吾尔族神经症患者视觉事件相关电位P300的异同。方法:选97例神经症患者作为神经症组(汉族48例,维族49例),99例健康者作为对照组(汉族45例,维族47例),对所有入组者均进行视觉事件相关电位P300检测并比较。结果:两组中汉族和维吾尔族神经症患者的靶N2潜伏期、靶P3潜伏期及波幅、非靶P2波幅差异均无统计学意义(P均>0.05);与正常对照组比较,汉族与维吾尔族神经症患者的靶N2潜伏期均延长(P均<0.05),靶P3潜伏期均延长且波幅降低(P均<0.05),非靶P2波幅均降低(P<0.05)。结论:汉族与维吾尔族神经症患者的视觉事件相关电位P300差异无统计学意义;神经症患者的视觉事件相关电位P300有多项指标变化。

【Abstract】 Objective: To compare the visual event-related potential P300 between the Han and the Uighur patients with neurosis. Method: 97 cases of neurosis patients (48 Han and 49 Uighur) were served as neurosis group,and 99 healthy adults (45Han and 47 Uighur) as control group. The visual event-related potential P300 was tested in all the people. Results: The Han and Uighur people showed no significant differences in latencies of target N2,target P3 and amplitudes of target P3,non-target P2 in both the neurosis group and control group (all P > 0. 05) . Compared with the control group,the latencies of target N2、target P3 were prolonged significantly and amplitudes of target P3,non-target P2 were reduced significantly in the neurosis group (all P <0. 05) . Conclusion: There are no significant differences in visual event-related potential P300 between the Han and Uighur patients with neurosis,but the neurosis patients were different on visual event-related potential P300 indices from normal.

  • 【文献出处】 临床精神医学杂志 ,Journal of Clinical Psychiatry , 编辑部邮箱 ,2010年04期
  • 【分类号】R749.7
  • 【下载频次】63
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