【摘要】 目的:探讨湖北荆门地区变应性鼻炎和变应性哮喘患者常见变应原分布情况,及主要变应原尘螨的致敏状况,为荆门地区变应性疾病的流行病调查、临床诊断治疗及预防提供科学依据。方法:对425例疑似变应性鼻炎和哮喘的患者,采用10种常见的标准化变应原试剂行皮肤点刺试验和特异性IgE检测,按年龄分为儿童组和成人组,比较2组变应原阳性率分布上的差异和尘螨变应原2种检测方法的相关性。结果:425例疑似变应性鼻炎和哮喘患者中298例为阳性反应,其中伴变应性哮喘89例。屋尘螨和粉尘螨阳性率最高,分别为292例、289例,其次分别为艾蒿45例、豚草31例、真菌Ⅰ19例、真菌Ⅱ15例、春季花粉Ⅱ14例、多价兽毛14例、春季花粉Ⅰ9例、多价羽毛3例。儿童组粉尘螨、屋尘螨皮肤试验和SIgE检测有很好的相关性,其强阳性率明显高于成人组。结论:尘螨为湖北荆门地区变应性鼻炎和哮喘最主要的变应原。更多还原

【Abstract】 Objective:In order provide important evidences for epidemiologic survey,clinical diagnosis,treatment and preservation of allergic diseases in this area,we investigate the distribution of the common allergens in allergic rhinitis and allergic asthma in Jingmen area and the sensitization condition of the major allergen house dust mite.Method:Four hundred and twenty-five patients with suspected allergic rhinitis and asthma in our area accepted skin prick tests of 10 standard allergen agents and specificity IgE detection. The different positivity ratios of allergens in different age groups were compared and the correlation between the two different technique methods testing the dust mite allergen was analyzed.Result:Among 425 patients with suspected allergic rhinitis and asthma in our area, 298 patients were positive and 89 patients suffered a combinated allergic asthma. House dust mite(292 cases) and dermatophagoides farinae(289 cases) were the commonest allergens. The other common allergens were mugwort (45), ragweed (31), fungusⅠ(19),fungusⅡ(15), spring-pollenⅡ(14), poly-animal hair(14), spring-pollenI(9),poly-feather(3). There was a correlation between skin test and sIgE test for house dust mite, dermatophagoides farinae in children group, and the positivity ratios were significantly higher than the adults group.Conclusion:Dust mite is the most important allergen in allergic rhinitis and asthma in Jingmen.更多还原