【摘要】 目的:探讨不同途径水合氯醛给药在小儿口腔治疗前的镇静效果。方法:对120例2～4岁无法有效配合治疗的患儿随机分为两组于口腔治疗前采取10%水合氯醛口服和10%水合氯醛灌肠而后进行口腔治疗。结果:口服组发生胃肠道反应的有13例,灌肠组0例。两组比较有统计学意义(P<0.01)。灌肠组药物起效时间明显快于口服组,两组比较有统计学意义(P<0.01)。镇静效果灌肠组优于口服组,两组比较有统计学意义(P<0.01)。镇静维持时间两组有明显差异(P<0.01)。结论:对于行为管理无效的小儿口腔治疗前采用水合氯醛镇静是一种安全有效的方法,若能采取灌肠则比口服效果更佳,从而为不能配合的患儿的口腔治疗提供较好的技术支持。更多还原

【Abstract】 Objective:To explore the sedative effect of chloral hydrate administration given in different ways for children with oral pre-treatment.Methods:120patients with 2-4years of age who were not cooperative were randomly divided into two groups before oral treatment.One group was given 10%chloral hydrate orally and the other was given 10%chloral hydrate by coloclysis and then carry out the oral treatment.Results:In oral group,gastrointestinal reactions occurred in 13cases,while in other group 0case.It was statistically significant(P<0.01).In coloclysis group,the onset time of drugs was faster than that of the oral group.It was statistically significant(P< 0.01).The coloclysis group was better than oral group in the sedative effect of the drug,which was statistically significant(P<0.01).There was distinct difference between the duration of sedative effect of the drug in these groups(P<0.01).Conclusion:For the uncooperative children,it is a safe and effective method to administer chloral hydrate for sedative purpose before oral treatment.But chloral hydrate given by coloclysis is better than that given by oral administration and thus providing agood technical support for the uncooperative children with oral therapy.更多还原