【摘要】 目的观察蚌埠市部分单位人员乙型肝炎病毒感染情况,初步分析各年龄段感染率,为了解现阶段乙肝感染情况提供参考数据。方法将受检者按年龄从小到大分成5组;采用酶联免疫吸附试验(ELISA)检测血清标本,并将结果按HBsAg阳性和阴性、抗-HBs阳性和阴性以及乙肝病毒感染的不同模式进行统计学分析。结果 16～25年龄组HBsAg阳性率最低为4.69%,远低于其他年龄组,差异有统计学意义(P<0.01),而抗-HBs阳性率高于其他年龄组,差异有统计学意义(P<0.05);16～25岁和26～35岁年龄组大三阳模式分别为29.27%、26.67%,高于其他组,差异有统计学意义(P<0.05)。结论青年人具有保护性抗体人数比例增加,乙型肝炎的感染率有所下降,但多为病毒复制活跃期,其血清具有较强的传染性。更多还原

【Abstract】 Objective To investigate the hepatitis B virus carriers in some units of Bengbu,and preliminary analysis of the infection rate in different age groups was conducted so as to provide evidence for understanding the situation of infectious hepatitis B virus at present stage. Methods All of the people were divided into five groups according to their age. The serum specimens were detected by ELISA,and the results were statistically analyzed according to the positive or negative HBsAg,HBsAb and the different serological patterns.Results The rate of HBsAg+ was lower and the rate of HBsAb+ was higher in 16～25 age group than that of others (P<0.05). The rate of HBsAg+,HBeAg+,HBcAb+ (pattern①) in 16～25 age group(29.27%) and 26～35 age group(26.67%) was higher than that of others(P<0.05). Conclusion The rate of HBsAb+ in the younger was increased,while the rate of infection was decreased,but most was active in HBV replicating and is of a strong infection in their serum.更多还原