【摘要】 目的:探讨维吾尔族和汉族内瘘术后血栓形成的临床因素。方法:根据血栓形成标准回顾分析维吾尔族和汉族透析患者内瘘术后4周内血栓形成病例,分为血栓组与非血栓组。分析两组的相应的临床指标(种族、性别、年龄、病因、血红蛋白、凝血功能、血脂等)与血栓形成的关系。结果:2005年1月～2009年11月符合纳入标准的内瘘手术患者共229例,术后4周内血栓发生率为7.0%。其中汉族患者血栓发生率为5.0%(9/189),维吾尔族患者发生率为14.5%(7/49),两者间差异有统计学意义(χ2=5.1,P=0.024)。维吾尔族脂蛋白(a)水平明显高于汉族[(296.7±211.5)mg/L vs(245.5±159.8)mg/L,t=5.8,P=0.017]。血栓组脂蛋白(a)水平较非血栓组高[(366.7±271.0)mg/L vs(250.5±161.9)mg/L,P=0.015]。结论:维吾尔族患者内瘘术后早期血栓发生率高于汉族,可能与脂蛋白(a)高有关。更多还原

【Abstract】 Objective:To analyse the cause of early thrombosis in internal arteriovenous after operation among Uygur nationality and Han nationality.Methods:We retrospectively analyzed the clinical data of hemodialysis patients amomg Uygur nationality and Han nationality,who were divided into thrombosis group and non-thrombosis group based on early thrombosis diagnostic criteria.The impact of clinical data including the nationality,gender and age,as well as the etiological factors,hemoglobin,thrombotest,lipid,were analyzed on early thrombosis in internal arteriovenous fistula.Results:According to the inclusion criteria,229 cases with internal arteriovenous fistula were studied between January,2005 and November,2009,the early thrombosis rate was 7.0%,out of which the early thrombosis rate is 5.0%(9/180)in Han people,while in Uygur nationality people,the rate is 14.3%(7/49),the result was statistically different(χ2=5.1,P=0.024)The level of lipoprotein(A) in Uygur nationality people is markedly higher than the level in Han people [(296.7±211.5)mg/L vs(245.5±159.8)mg/L,t=5.8,P=0.017].The level of lipoprotein(A) is higher in thrombosis group than the level in non-thrombosis [(366.7±271.0)mg/L vs(250.5±161.9)mg/L,P=0.015].Conclusion:The early thrombosis rate in the Uygur nationality people is higher than the rate in the Han people,which may be associated with the high-lipoprotein(A).更多还原