【摘要】 丙型肝炎严重威胁人类健康,并在全球范围内流行,目前尚无有效办法预防和治疗丙型肝炎病毒感染,胞苷酸鸟苷(CpG)寡脱氧核苷酸(CpGODN)作为一类较强的免疫调节佐剂,能够广泛诱导交叉中和性抗体和细胞免疫反应,对丙型肝炎病毒感染具有治疗作用。本文对以CpGODN为佐剂的丙型肝炎生物治疗研究进展予以综述。更多还原

【Abstract】 Hepatitis C virus(HCV)infection is an important infectious disease threatening human health worldwide.No vaccine is currently available for prevention and cure of HCV infection.Cytidine phosphate guanosine oligodeoxynucleotides(CpG ODN),as the potent regulators of immunity,can induce broad cross neutralizing antibodies,strengthen the cellular immune responses and may serve as a candidate for treatment of HCV infection.Research progress in CpG ODN for treating hepatitis C virus infection is reviewed.更多还原