【摘要】 目的探讨食管支架植入术后贴覆不良现象(ESDP)的发生及相关危险因素。方法收集98例接受食管支架植入术的恶性肿瘤患者,对术后7例发生ESDP者,选取9个危险因素,包括:年龄、性别、梗阻部位、是否伴食管-气管瘘、既往有无外科手术史、放疗史、梗阻远端扩张程度、是否为喇叭形支架、支架覆膜与否,以Logistic回归分析危险因素。结果本组ESDP发生率为7.14%,主要表现为术后不同程度的吞咽困难或呛咳,并伴有持续胸痛,以进食时加重。食管造影可见支架内对比剂通过顺畅,但在支架与食管壁之间对比剂明显滞留。Logistic回归分析显示阳性因素为既往放疗病史(P=0.005)及梗阻远端扩张程度(P=0.017)。结论ESDP为食管支架植入术后并发症之一。对于既往有放疗病史且梗阻上方明显扩张者,需慎行食管支架植入术。更多还原

【Abstract】 Objective To evaluate the conditions and risk factors of esophageal stent dys-seal phenomenon(ESDP).Methods Ninety-eight patients with malignant esophageal obstruction underwent metallic stent placement and 7 patients with ESDP were analyzed.The possible contributing factors,including age,gender,obstruction segment,esophagorespiratory fistula,surgical intervention,radiotherapy,the degree of upper obstruction segment expansion,stent with bell-mouth,application of covered stent were investigated.All factors mentioned above were analyzed with Logistic regression analysis.Results ESDP was observed in 7 patients(7/98,7.14%) and defined as a space between the esophageal wall and the proximal part of stent without contrast agent obstruction within stent.The clinical situations of patients with ESDP included dysphagia,bucking and constantly chest pain,especially at foodintake.The results of Logistic regression analysis indicated radiotherapy(P=0.005) and the degree of upper obstruction segment expansion(P=0.017) were significantly correlated with ESDP.Conclusion ESDP is one of the complications after esophageal stent placement.It is prudent to implant esophageal stent for those patients with radiotherapy and significant upper obstruction segment expansion.更多还原