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阿司匹林凝胶剂的制备及质量控制
Preparation and quality control of asprin gel
【摘要】 目的:制备阿司匹林凝胶剂。方法:以卡波姆水凝胶为基质制备阿司匹林凝胶剂,采用高效液相色谱法进行含量测定。结果:阿司匹林在280nm处有最大吸收,在16~80μg/ml浓度与吸收度线性关系良好。含量测定平均回收率为99.85%,RSD=1.2%(n=3)。结论:阿司匹林凝胶剂性质稳定,制备简单,易于质量控制,适用于医院配制及临床应用。
【Abstract】 Objective To prepare asprin gel.Method The carbormor hydrogel has been chosen to make asprin gel.And the HPLC method was employed to determine the content.Results Asprin gel showed a maximum absorbance at 280 nm in solution and a good liner relationship with absorbance over the range of 16 ~ 80 μg/ml.Conclusion Asprin gel is stable and with convenient usage as the advantage,easy to control,which means a reliable and proper preparation for the hospital and it is a useful medicine for clinic.
- 【文献出处】 吉林医学 ,Jilin Medical Journal , 编辑部邮箱 ,2010年22期
- 【分类号】R94
- 【被引频次】1
- 【下载频次】503