【摘要】 目的研究血清降钙素原(PCT)和C-反应蛋白(CRP)在重症急性胰腺炎(SAP)患者中的表达,探讨其在临床中的应用价值。方法用化学免疫发光法和免疫比浊法,分别检测40例SAP感染组、20例SAP非感染组患者和40例健康人对照组血清PCT和CRP水平,并进行回顾性分析。结果 PCT、CRP在SAP感染组和非感染组中的表达显著高于对照组(P<0.01);SAP感染组CRP表达比非感染组增高(P<0.05)。结论 PCT、CRP表达显著增高可能与重症急性胰腺炎患者是否感染有关。PCT、CRP的高表达,可作为SAP的临床诊断、治疗及预后判断的重要参考指标。更多还原

【Abstract】 Objective To investigate the expressions of Procalcitonin(PCT) and C-reactive Protein(CRP) and detect the value of their clinical application in Severe Acute Pancreatitis(SAP). Methods The study included 40 cases of SAP infection as experimental group,20 cases of SAP non infection and 40 cases of normal as control group.The expressions of PCT and CRP were detected by applying the chemical luminescence immune method and Immunoturbidimetry,and were analysed retrospectively.Results Comparisons of the SAP in infection group,non infection and normal group showed that there were significant upregulation of the expressions in PCT and CRP(P<0.01).The expression of CRP in SAP infection and non infection groups also has significant difference(P<0.05).Conclusions The significant upregulation of PCT and CRP may be correlated with SAP infection,or non infection.The high expression of PCT and CRP may be important reference indicators in clinical diagnosis,treatment and prognosis of SAP.更多还原