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男性暴力行为的脑灰质结构磁共振研究
Morphological Changes of Cerebral Gray Matter in Violent Males
【摘要】 目的研究暴力行为相关的脑灰质密度的情况。方法使用磁共振成像系统对男性暴力行为组(n=20)和与之相匹配的正常男性(n=21)进行脑结构扫描,并采用基于像素的形态学测量(VBM)的方法对数据进行分析。结果暴力组额中回、左楔前叶、右侧顶下小叶、颞叶梭状回及右颞中回、双侧小脑的灰质密度低于正常对照组,而左颞上回(BA38)及右海马旁回的密度高于正常对照组(P<0.001)。结论暴力行为者存在脑结构的损害。主要包括前额叶、颞叶和楔前叶,它们的异常可能是暴力行为的神经结构基础。
【Abstract】 Objective To investigate the morphological changes of cerebral gray matter in violent people.Methods Voxel based morphometry in conjunction with statistical parametric mapping was applied to the structural magnetic resonance images of 20 violent males and 21 normal controls.Results Compared with the controls,the cerebral gray matter concentrations were significantly decreased in the bilateral middle frontal cortex,right inferior parietal lobule and bilateral fusiform cortex,left precuneus and left cerebellum of violent people.Condusion The results suggest the gray matter of the prefrontal cortex,precuneus and cerebellum is lost in some degree in violent people.
- 【文献出处】 南华大学学报(医学版) ,Journal of University of South China(Medical Edition) , 编辑部邮箱 ,2010年05期
- 【分类号】B849;R445.2;R741.02
- 【被引频次】4
- 【下载频次】123