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电针对内脏痛大鼠镇痛作用的实验研究

Experimental research of electroacupuncture analgesia on visceral pain in rats

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【作者】 徐克达梁桃薄挽澜田德安

【Author】 XU Ke-da,LIANG Tao,BO Wan-lan,et al(Department of Digestive Diseases,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

【机构】 华中科技大学同济医学院附属同济医院消化内科哈尔滨医科大学第一临床医学院消化内科

【摘要】 目的探讨电针对内脏痛大鼠疼痛行为的影响。方法将大鼠随机分为Con组、Con+EA组、VP组和VP+EA组,每组8只。将5%的福尔马林溶液40μL注射入大鼠结肠内制作内脏痛模型。制作模型前预先电针刺"足三里"、"伏兔"穴,强度以大鼠胡须抖动但不出现挣扎为准。观察并计算内脏痛评分。结果 VP组大鼠在注射福尔马林后立即出现明显的内脏痛行为,而VP+EA组内脏痛行为时间推迟,疼痛明显减弱(P<0.05)。结论电针对内脏痛大鼠具有镇痛作用。

【Abstract】 Objective To explore the effect of electroacupuncture on the visceral pain in rats.Methods Rats were randomly divided into the Con group,Con+EA group,VP group and VP+EA group,n=8.40 μL 5% formalin solution was injected into the rat colon to establish a visceral pain model.Electric acupuncture at "Zusanli","V Rabbit" point was given in advance of model establishment,with strength of rats subject to whiskers jitter but does not struggle.Visceral pain score was calculated.Results VP rats immediately appeared visceral pain behaviors after the injection of formalin,whereas,in VP+EA groups,visceral pain behaviors was delayed,as well as pain significantly decreased(P<0.05).Conclusion Electroacupuncture has the analgesic effect on visceral pain in rats.

【关键词】 电针内脏痛镇痛
【Key words】 electroacupuncturevisceral painanalgesia
  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,2010年05期
  • 【分类号】R245.31
  • 【被引频次】6
  • 【下载频次】189
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