【摘要】 报道了标题化合物的制备方法。该方法首先用2-萘乙酮与盐酸羟胺反应生成中间体2-萘乙酮肟,然后该中间体在多聚磷酸催化下发生Beckmann重排反应生成2-乙酰萘胺,最后通过盐酸脱去乙酰基得标题化合物。该制备方法具有合成过程操作方便、分离提纯程序简单、生产安全等优点,特别适合于常规实验室的制备。更多还原

【Abstract】 A convenient method for preparation of 2-naphthylamine has been described.Firstly,treatment of 2-acetonaphthone with hydroxylammonium chloride in the presence of sodium acetate gave the intermediate 2-acetonaphthone oxime.Then rearrangement of 2-acetonaphthone oxime in the presence of polyphosphoric acid afforded 2-acetamidonaphthalene.Finally deacetylation of 2-acetamidonaphthalene with concentrated hydrochloric acid in ethanol gave 2-naphthylamine.This method has many advantages such as the facilitated operation,easy isolation or purification of the product,and working safety,which are strongly suitable for preparation in a standard laboratory.更多还原