【摘要】 首次利用动态光谱指端透射法进行了人体红细胞无创测量的研究.对28名健康志愿者进行了在体测量,选用偏最小二乘法(PLS)对获取的动态光谱数据和红细胞实测值进行建模分析,得到定标集和验证集的相关系数分别为0.9193和0.9058,验证集的相对误差最大为7.96%,平均相对误差为6.21%.结果表明,动态光谱法可以有效地克服个体差异等对光谱测量的影响,较准确地进行人体红细胞含量的测量,是一种比较好的血液成分无创测量方法.更多还原

【Abstract】 Dynamic spectrum (DS) method was used to measure non-invasively human erythrocyte content for the first time.In vivo measurements were carried out to 28 healthy volunteers,and parital least-squares(PLS) regression was used to establish the calibration model of subjects’ erythrocyte content values against DS data.The correlation coefficients were 0.9193 and 0.9058 for calibration set and validation set,respectively.The biggest relative error of validation is 7.96%,and the average relative error is 6.21%.Measurement results show that the influences of individual differences on spectra can be decreased effectively by DS method.This method can measure accurately human erythrocyte content and it is a promising method for non-invasive blood analysis.更多还原