节点文献

二至丸对D-半乳糖致衰老模型小鼠NO、SOD影响的实验研究

Experimental Study of Erzhiwan on NO、SOD in Aged Mice Resulting from D-galactose

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 王明娟任慧玲任汉阳

【Author】 Wang Mingjuan,Ren Huiling,Ren Hanyang Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008

【机构】 河南中医学院

【摘要】 目的:探讨二至丸对亚急性衰老模型小鼠的抗氧化作用,为进一步研究其抗衰老作用提供依据。方法:用D-半乳糖法制备小鼠亚急性衰老模型,观察其全血、肝组织中SOD、NO的含量及二至丸对其影响。结果:实验药物组与模型组相比,小鼠全血、肝组织中的SOD活力增强,NO的含量减少,且呈剂量依赖关系。结论:二至丸发挥抗衰老作用可能与其具有升高SOD活力和降低NO的含量相关。

【Abstract】 Objective:To explore the antioxidation effects of Erzhiwan,for further research to provide the basis of its antiaging effects. Methods:Preparation the subacute aging model mice by using the Dgalactose. We observed it’s indexes such as serum and liver tissue SOD,NO content and Erzhiwan influnce on it. Results:The experimental group compared with the aging model group,serum and liver tissue SOD activity increased,NO levels decrease,and show dose dependence. Conclusion:Erzhiwan to play its role in anti -aging may be associated with increase the SOD activity and reduce the levels of NO related.

【基金】 河南省科技攻关项目(编号:0224630121)
  • 【文献出处】 中医学报 ,China Journal of Chinese Medicine , 编辑部邮箱 ,2010年03期
  • 【分类号】R285.5
  • 【被引频次】8
  • 【下载频次】202
节点文献中: 

本文链接的文献网络图示:

本文的引文网络