【摘要】 目的:了解2型糖尿病患者干眼症相关指标的变化情况,以及与血糖水平的相关关系。方法:对35例(70眼)2型糖尿病患者和38例(76眼)正常健康人群行泪膜破裂时间测定、基础泪液分泌试验以及角膜荧光素染色,并分析与患者血糖水平的相关性。结果:2型糖尿病患者的泪膜破裂时间、基础泪液分泌值明显低于正常人群(P<0.01),而角膜荧光素染色评分明显高于正常人群(P<0.01)。进一步分析显示2型糖尿病患者血糖水平与泪膜破裂时间、基础泪液分泌值以及角膜荧光素染色评分之间存在明显相关关系(P<0.05)。结论:2型糖尿病患者泪膜破裂时间缩短、基础泪液分泌值减少以及角膜荧光素染色评分升高,控制好血糖水平能够改善干眼症的相关指标。更多还原

【Abstract】 Objective:To investigate the changes of xerophthalmia related indexes,and their correlation with glucose level in patients with type 2 diabetes.Methods:Tear film break-up time(BUT),basal tear secretion test(Schirmer I test,Sit)and corneal fluorescein staining(FLS)were detected in 70 eyes of 35 patients with type 2 diabetes and 76 eyes of 38 normal healthy people to analyzed the correlations of these indexes and glucose level in patients with type 2 diabetes.Results:The value of BUT and Schirmer I test in patients with type 2 diabetes were significant lower than that in normal healthy people(P<0.01),however,the FLS scores of patients were significant higher than that of normal people(P<0.01).Further analysis showed that there were significant correlations between BUT,the value of Schirmer I test,FLS scores and glucose level in patients with type 2 diabetes(P<0.05).Conclusions:The value of BUT and Schirmer I scores in patients with type 2 diabetes decreases while FLS scores increases.Good control of glucose level can improve these xerophthalmia related indexes.更多还原