【摘要】 目的:探讨小儿短小手术患儿应用瑞芬太尼复合异丙酚麻醉的临床效果。方法:选择需做小儿短小手术的患儿48例,ASAⅠ～Ⅱ级,年龄4～12岁,按年龄和麻醉药物分为4组(n=12):A组4～7岁,Aa组8～12岁,瑞芬太尼复合异丙酚麻醉;B组4～7岁,Bb组8～12岁,氯胺酮复合异丙酚麻醉。A和Aa组静脉泵入静脉泵入异丙酚4mg.kg-1.h-1和瑞芬太尼0.1μg.kg-1.min-1。B和Bb组异丙酚4mg.kg-1.h-1和氯胺酮3mg.kg-1.h-1。结果:4组SP、DP、HR、RR均较麻醉前降低但在正常范围(P<0.05);与B和Bb组比较,A和Aa组RR降低,术中体动和术后躁动发生率降低,苏醒时间和意识恢复时间缩短(P<0.05)。结论:瑞芬太尼复合异丙酚用于小儿短小手术患儿可产生良好的麻醉效果,且具有术中生命体征稳定、血液动力学平稳,不良反应发生率低及术后苏醒迅速等优点。更多还原

【Abstract】 Objective:To evaluate the clinical efficacy and safety of remifentanil combined propfol in infant anesthesia for minorsurgeries.Methods:48 infants undergoing minor surgeryies with were randomly divided into four groups,12 patients each group.The A group from 4-7 year old and Aa group from 8-12 year old were anesthetized by remifentanil combined with propfol.The B group from 4-7 year old and Bb group from 8-12 year old were anesthetized by remifentanil combined with ketamine.Anesthesia was maintained with 0.2 μg·kg-1·min-1 remifentanil combined with 4 mg·kg-1·min-1 propfol micropump infusion in group A and Aa,but in group B and Bb with 3 mg·kg-1·min-1 ketamine micro pump infusion.Hemodynamic parameters were observed continuously.Recovery time and anesthesia effects (evaluated by surgeon) were also analyzed.Results:SP,DP,HR and RR decreased after anesthesia,but all was in normal range.The RR and the time of analepsia and consciousness recovery of group A and Aa significantly decreased than group B and Bb (P<0.05).The incidence rate of body action in operation and restlessness after operation of group A and Aa significantly decreased than group B and Bb (P<0.05).Conclusion:Remifentanil combined with propfol in infant anaesthesia for minor surgeries,has the advantages such as stable vital signs during operation,rapid awake and low rate of adreuse reactions.更多还原