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急性脑梗死患者血清高敏C反应蛋白水平测定
Determination of serum high-sensitivity C-reactive protein level in patients with acute cerebral infarction
【摘要】 目的:测定急性脑梗死患者血清高敏C反应蛋白(hs-CRP)水平。方法:急性脑梗死患者115例,其中轻度、中度及重度血栓性脑梗死分别为15、56和39例,腔隙性脑梗死5例。选择80例门诊体检健康者为正常对照。采用免疫透射比浊法测定血清hs-CRP水平。结果:①随脑梗死程度的加重,hs-CRP水平及异常率升高(F=551.000,χ2=166.510,P均<0.001)。②血清hs-CRP水平异常者脑梗死预后不良(χ2=24.880,P<0.001)。结论:hs-CRP水平是判断急性脑梗死患者病情和预后的良好指标。
【Abstract】 Aim:To determine the serum high-sensitivity C-reactive protein(hs-CRP) in patients with acute cerebral infarction(ACI).Methods:A total of 115 cases of ACI including 110 cases of thrombotic cerebral infarction (mild:15 cases;moderate:56 cases;severe:39 cases) and 5 cases of lacunar cerebral infarction.Eighty outpatients who accepted health examination were normal controls.The content of hs-CRP was determined using immunity transmission nephelometry method.Results:With the development of ACI,hs-CRP level and abnormal rate increased(F=551.000,χ2=166.510,P<0.001).The patients with abnormal serum hs-CRP had bad outcome (χ2=24.880,P<0.001).Conclusion:hs-CRP is an ideal indicator of disease condition and prognosis of ACI.
【Key words】 high-sensitivity C-reactive protein; cerebral infarction; artery atherosclerosis;
- 【文献出处】 郑州大学学报(医学版) ,Journal of Zhengzhou University(Medical Sciences) , 编辑部邮箱 ,2010年03期
- 【分类号】R743.33
- 【被引频次】9
- 【下载频次】121