【摘要】 目的探讨中年高血压患者记忆和认知功能障碍的特点及其血压参数、记忆、认知功能障碍的相关性。方法采用临床记忆量表、简易智能精神状态量表(MMSE)、Zung抑郁自评量表对90例中年高血压患者和46例健康体检者进行测试。结果 (1)中年高血压组患者的定向力、指向记忆、联想学习、图像自由回忆、人像特点联系回忆、总量表分和记忆商(MQ)各项的等值量表分与对照组相比差异有统计学意义(P<0.05)。(2)平素最高舒张压、最高脉压与短时记忆正相关(P<0.05),平素最低收缩压,最低平均动脉压与语言能力负相关(P<0.05),高血压病史与定向力负相关(P<0.01)。结论 (1)中年高血压患者存在明显的记忆和认知功能障碍,主要表现为听觉记忆、视觉记忆以及听觉和视觉记忆的结合等功能障碍。(2)高血压史、血压参数对短时记忆和认知功能有影响。更多还原

【Abstract】 Objective To study memory and cognition impairment in middle-age patients with hypertension,and explore the correlation between blood parameter with memory and cognitive impairment.Methods Ninety middle-age patients with hypertension and 46 health volunteers were measured with clinical memory scale,mini-mental state examination scale and Zung self-rating depressive scale. Results Orientation,direct memory,associational learning,image free recall,portrait feature association recall,total scale and every equivalence scale of memory quotient were worse than the health volunteers. The normally highest diastolic blood pressure and highest pulse pressure were positively correlated with short-term memory. The normally lowest systolic blood pressure and lowest mean arterial blood pressure were negatively correlated with linguistic capacity. The hypertension history was negatively correlated with direct memory.Conclusion There are significant memory and cognitive impairment in middle-age patients with hypertension,mainly impairment in acoustic memory,visual memory and combination with these memories. The hypertension history and blood parameter are correlated with short-term memory and cognitive impairment.更多还原