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小剂量尿激酶联合低分子肝素治疗短暂性脑缺血发作疗效观察

Efficacy of cooperative treatment with low dose of UK and low weight heparin on TIA

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【作者】 李军民

【Author】 Li Junmin.The First People’s Hospital of Yiyang,Yiyang 471600,China

【机构】 河南宜阳县人民医院

【摘要】 目的观察小剂量尿激酶(UK)联合低分子肝素钙治疗短暂性脑缺血(TIA)的临床效果。方法将60例TIA患者随机分为治疗组(30例)与对照组(30例),治疗组给予小剂量UK联合低分子肝素钙,疗程10天,两组均常规使用胞二磷胆碱、阿司匹林、尼莫地平、洛伐他汀及对症治疗。结果治疗组基本治愈20例,有效7例,无效3例,总有效率为90%。对照组,基本治愈8例,有效11例,无效7例,恶化4例,总有效率为63%,两者有显著差异(P<0.01)。结论小剂量UK联合低分子肝素钙疗法,具有易用、高效、不良反应小等优点,值得临床推广使用。

【Abstract】 Objective To observe the efficacy of cooperative treatment with low dose of UK and low weight heparin on TIA.Methods Sixty patients were randomly divided into treatment group and control group,each with thirty patients.The patients in treatment group were given low dose of UK and calcium low weight heparin for 10 days,while the controls group given Sanchi Saponin by venous also for 10 days.Other routine treatment,such as corenalin,aspirin,nimodipine and lovastatin,were same between the two groups.Results Total effective rate in treatment groups was 90%,with 20 cases cured,7 cases valid and 3 cases invalid,while 63% in the controls,with 8 cases cured,11 cases valid,7 cases invalid,and 4 cases worsened.There was significant difference between the two groups(P<0.01).Conclusion It is effective to treat TIA cooperatively with low dose of UK and calcium low weight heparin.

  • 【文献出处】 中国实用神经疾病杂志 ,Chinese Journal of Practical Nervous Diseases , 编辑部邮箱 ,2010年11期
  • 【分类号】R743.31
  • 【被引频次】6
  • 【下载频次】38
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