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莪术油注射液的制备及体外抗PRRSV作用试验

Preparation of Oleum Curcumae Aromaticae Oil Injection and Its In Vitro Effects on Anti-PRRSV

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【作者】 徐端红崔保安王学兵张红英魏战勇张爱芹况玲

【Author】 XU Duan-hong1,2,CUI Bao-an2,WANG Xue-bing2,ZHANG Hong-ying2,WEI Zhan-yong3,ZHANG Ai-qin2,KUANG Ling1 (1.College of Animal Medicine,Xinjiang Agricultural University,Urumqi 830052,China;2.Henan Agricultural University,Zhengzhou 450002,China;3.Animal Food Safety Key Laboratory in Henan Province,Zhengzhou 450002,China)

【机构】 新疆农业大学动物医学学院河南农业大学河南省动物性食品安全重点实验室

【摘要】 为筛选抗猪繁殖与呼吸综合征病毒(PRRSV)的中药,制备了莪术油注射液,并以其为试验药物,同时以利巴韦林注射液作为对照药物,观察在体外细胞上对PRRSV的作用效果。结果表明,自最大安全浓度(质量浓度)作倍比稀释后,二者对PRRSV均具有一定的抑制、杀灭和阻断作用。其中,莪术油注射液对PRRSV的杀灭作用较为突出,利巴韦林注射液杀灭和抑制作用均较为显著。

【Abstract】 For the screening of medicines anti-porcine reproductive and spiratory syndrome virus(PRRSV),Oleum curcumae aromaticae oil injection was prepared as the investigational drug to observe its in vitro effect on PRRSV.For a negative control,ribavirin injection was used.The results showed that,since the maximum safe concentration to do multiple proportion dilute,they had a certain degree of inhibition,killing,and blocking effects on PRRSV.Among them,the killing effect of oleum curcumae aromaticae oil injection was more prominent and ribavirin injection had a significant effect on inhibitory action and killing.

【基金】 郑州市科技创新团队项目(10C×TD148)
  • 【文献出处】 河南农业科学 ,Journal of Henan Agricultural Sciences , 编辑部邮箱 ,2010年10期
  • 【分类号】S859.79
  • 【被引频次】10
  • 【下载频次】180
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