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头孢菌素C发酵过程中蛋氨酸加量对菌丝形态及效价的影响
The Influence of Methionine Quantity to Hyphae Form and Fermentation Level in Cephalosporin C Fed-batch Fermentation
【摘要】 通过调整头孢菌素C发酵底物中蛋氨酸的浓度,对比不同时期的菌丝形态及效价,确定了蛋氨酸加量在8‰时,头孢霉菌菌丝分化快速、均匀,并且在此浓度下发酵效价达到最高水平。
【Abstract】 Through adjusting the substrate concentration of methionine in cephalosporin C fermentation,and contrasting different periods of hypha form and fermentation level.It can be learned that the quantity in 8‰ methionine of the substrate concentration effected fast and evenly morphological differentiation,and the fermentation level was the highest level.
【关键词】 头孢菌素C;
发酵;
蛋氨酸;
菌丝分化;
效价;
【Key words】 Cephalosporin C; fermentation; methionine; morphological differentiation; titer;
【Key words】 Cephalosporin C; fermentation; methionine; morphological differentiation; titer;
- 【文献出处】 河北化工 ,Hebei Chemical Engineering and Industry , 编辑部邮箱 ,2010年01期
- 【分类号】TQ465
- 【被引频次】4
- 【下载频次】208