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血清肌钙蛋白T和肌红蛋白测定在急性心肌梗塞患者早期诊断中的意义
The Value of Serum Cardiac Troponin T and Myoglobin in Early Diagnosing Acute Myocardial Infarction
【摘要】 目的:探讨测定血清肌钙蛋白T(CTnT)和肌红蛋白(Mb)在急性心肌梗塞(AMI)患者早期诊断中的意义。方法:电化学发光法测定93例急性心肌梗死患者在发病后3h和24h血中肌钙蛋白T和肌红蛋白的水平,同时与正常对照组进行比较。结果:肌钙蛋白T在3h内阳性率显著低于肌红蛋白(P<0.05);24h阳性率达100%。结论:肌钙蛋白T是诊断AMI最佳的指标,同时联合检测肌红蛋白,可以提高临床早期诊断的可靠性,具有临床应用价值。
【Abstract】 Objective:To investigate the value of serum cardiac troponin T (CTnT) and myoglobin (Mb) in early diagnosing acute myocardial infarction.Method:The electrochemiluminescence was used to detect the levels of CTnT and Mb between 93 patients with acute myocardial infarction after onset for 3 hours and 24-hour and compared with those in the control group.Result:The positive rate of CTnT within onset for 3 hours was significantly lower than the positive rate of myoglobin (P <0.05),the 24-hour positive rate was 100%.Conclusion:The CTnT is the best indicator in diagnosing AMI,while the joint detection of myoglobin can improve the reliability of early diagnosis.
【Key words】 Acute myocardial infarction; Serum cardiac troponin T (CTnT); Myoglobin (Mb);
- 【文献出处】 河北医学 ,Hebei Medicine , 编辑部邮箱 ,2010年05期
- 【分类号】R542.22
- 【被引频次】37
- 【下载频次】397