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肺癌患者空气贮留与肺功能指数的相关分析

Correlation between air-trapping and pulmonary functional indexes in patients with lung cancer

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【作者】 王文秀高江峰李云霄李雯纪俊雨王新举章志华崔春祎王立强刘树芳

【Author】 WANG Wenxiu,GAO Jiangfeng,LI Yunxiao,et al. Department of Radiology,Hebei Chest Hospital,Shijiazhuang 050041, China

【机构】 河北省胸科医院放射科

【摘要】 目的探讨肺癌患者空气贮留与肺功能指数的相关性。方法对57例病理确诊为肺癌患者,使用螺旋CT分别进行了不同呼吸时相的连续容积数据模式扫描,对空气贮留进行评分,全部患者作了肺功能检查。结果肺癌患者空气贮留与小气道功能指标FEF25%(r=-0.51,P<0.05),FEF50%(r=-0.77,P<0.01)、RV(r=0.75,P<0.01)高度相关,与FEV1(r=-0.20,P>0.05)、FVC(r=-0.19,P>0.05)、FEV1/FVC(r=-0.35,P>0.05)不相关。结论肺癌患者的空气贮留与小气道功能指标有密切相关性。

【Abstract】 Objective To analyze the correlations between air-trapping and pulmonary functional indexes in patients with lung cancer. Methods 57 patients were diagnosed as lung cancer by pathology and scanned by spiral CT at the end inspiration and expiration with continuous volume scan mode. Expiration scans were scored at a lobar level for the areas of air-trapping. All the patients were performed pulmonary function tests ( PFT) . Results The small airways’functional indexes were negatively correlated with total air-trapping scores in FEF25% ( P < 0. 05) ,FEF50% ( P < 0. 01) and were positively correlated with RV ( P < 0. 01) . But there was no correlation in FEV1( P > 0. 05) ,FVC( P > 0. 05) ,FEV1 /FVC( P > 0. 05) . Conclusion There is a close correlation between air trapping and small airways’functional indexes in patients with lung cancer.

【关键词】 肺癌小气道病变肺功能
【Key words】 lung cancersmall airway lesionlung function
【基金】 河北省医学科学研究与发展基金项目(编号:20090268)
  • 【文献出处】 河北医药 ,Hebei Medical Journal , 编辑部邮箱 ,2010年18期
  • 【分类号】R734.2
  • 【被引频次】4
  • 【下载频次】37
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