【摘要】 目的探讨血清胱抑素C(Cys-C)的检测在肾病诊断中的价值。方法应用微粒子增强比浊法检测各种肾病患者的血清胱抑素C浓度,同时采用Jaffe法测定血清肌酐(Scr),并计算内生肌酐清除率(Ccr),并进行相关的统计分析。结果 Cys-C的水平随肾功能的减退而逐渐升高,在Ccr≥80ml/min的患者中,Cys-C异常率为5%,Scr异常率为0;在20ml/min≤Ccr<80ml/min的患者中,Cys-C异常率为68%,Scr异常率为53%;在Ccr<20ml/min的患者中,Cys-C与Scr的异常率均为100%。结论血清胱抑素C(Cys-C)是反映肾功能损害的早期敏感标志物,为临床及时发现早期肾病并对其作出诊断提供了判断依据。更多还原

【Abstract】 Objective To explore value of the applicability of cystatin C in diagnosing early in kidney diseases.Methods Serum cystatin C concentration was determined by particle-enhanced turbidimetry,serum creatinine (Scr) by Jaffe method and Creatinine clearance rate were measured.Results The level of serum cystatin C was gradually elevating along with the decrease of endogenous creatinine clearance.Conclusion Serum cystatin C is a early sensitive marker to reflect the kidney function injure,and provide judgment basis for diagnosing kidney diseases early.更多还原