【摘要】 目的观察盐酸氨基葡萄糖治疗膝骨关节炎的临床疗效。方法选择160例患者随机分成A、B两组,A组给予塞来昔布胶囊口服,疗程3周,联合盐酸氨基葡萄糖(奥泰灵)口服,疗程6周;B组给予塞来昔布胶囊口服,疗程3周,联合玻璃酸钠注射液膝关节腔内注射,疗程5周。比较两组的疗效。结果治疗后1周时有效率盐酸氨基葡萄糖组(40.0%)不如玻璃酸钠组(60.0%),但随治疗时间的延长,6周时盐酸氨基葡萄糖组治疗的总有效率(75.0%)与玻璃酸钠组(77.5%)相比无显著性差异(P<0.05)。结论盐酸氨基葡萄糖治疗膝骨关节炎安全、有效。更多还原

【Abstract】 Objective To observe the clinical efficacy of glucosamine hydrochloride in the treatment of knee osteoarthritis.Methods 160 patients with knee osteoarthritis were randomized into group A and group B.Patients in group A first took celecoxib capsules for 3 weeks and glucosamine hydrochloride capsules for 6 weeks in combination, with a total treatment course of 6 weeks.Patients in group B first took celecoxib capsules for 3 weeks,and were given sodium hyaluronate injection into their knees for 5 weeks in combination,with a total treatment course of 5 weeks.The efficacies of 2 groups were compared.Results The effective rate of group A(40.0%) was lower than that of group B (60.0%) after 1 week.There was no significant difference(P<0.05) of the overall effective rate between the 2 groups with group A(75.0%) and group B(77.5%) after 6 weeks.Conclusions Glucosamine hydrochloride is safe and effective in the treatment of knee osteoarthritis.更多还原