【摘要】 为了解A2a基因敲除小鼠的生物学物性,给研究心血管疾病及神经疾病提供部分基础资料,试验采用全自动生化分析仪及血细胞分析仪分别对60日龄C57BL/6、A2a雌雄小鼠的常用血液学指标及生化指标值进行检测,并测定了各小鼠的脏器。结果:C57BL/6和A2a小鼠血液的血小板计数、红细胞分布宽度差异显著(P<0.05)。C57BL/6和A2a小鼠的丙氨酸转氨酶、肌酸激酶差异显著(P<0.05),乳酸脱氢酶差异极显著(P<0.01),脏器系数无显著差异(P>0.05)。更多还原

【Abstract】 To obtain the information of characteristics of reproduction and growth of A2a mice and establish the normal hematological indexes and biochemical indexes,the normal Organ weight in SPF A2a knockout mice and C57BL/6 mice.The growth and reproduction performances including litter size,weanling rate,body length,body weight and organ weight were investigated in the A2a mice;20 male and 20 female SPF A2a mice and 20 C57BL/6 mice of 60 days sold were selected.The indexes of hematology,biochemistry and Organ coefficient of SPF A2a mice and that of C57BL/6 mice were measured by automatibiochemical and analyze.Results RDW and PLT of C57BL/6 mic were different from A2a mices(P<0.05),while the ALT and CK were lower in male mice than in females of A2a mice(P<0.05),CK were significant difference(P<0.01).It were differences of organ coefficient.更多还原