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鲍曼不动杆菌肺部感染的临床特点及耐药性分析

Clinical characteristics and drug resistance of Acinetobacter baumannii pulmonary infection

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【作者】 孙雪皎王豫平

【Author】 SUN Xue-jiao,WANG Yu-ping(The Fifth Affiliated Hospital,Guangxi Medical University,Liuzhou 545001,China)

【机构】 广西医科大学第五附属医院

【摘要】 目的分析和总结鲍曼不动杆菌肺部感染的临床特点及耐药规律。方法对2006年6月-2008年6月间住院的65例鲍曼不动杆菌肺部感染患者临床资料进行分析。结果鲍曼不动杆菌肺部感染在综合重症监护病房(ICU,41.54%)、神经内科监护病房(29.23%)、神经外科监护病房(10.77%)、呼吸内科(10.77%)较常见;对多种抗菌药物的耐药率>70%;感染患者大多为年老体弱、基础疾病多、住院时间长且接受各种侵入性操作、感染前反复使用2种以上抗菌药物者;部分病例合并其他病原菌感染,以铜绿假单胞菌(34.55%)及嗜麦芽窄食单胞菌(20.00%)较多。结论鲍曼不动杆菌肺部感染患者病情重,对抗菌药物耐药率高,掌握其临床特点、感染分布及耐药规律,对临床预防与治疗尤为重要。

【Abstract】 Objective To analyze the clinical characteristics and drug resistance of Acinetobacter baumannii(A. baumannii)pulmonary infection.Methods Clinical data of 65 cases of A.baurnannii pulmonary infections in a hospital from June,2006 to June,2008 were analyzed.Results The incidence rate of A.baumannii infections were high in general intensive care unit(ICU,41.54%),neurological ICU(29.23%),neurosurgical ICU(10.77%),and respiratory department(10.77%);Resistant rates to many kinds of antimicrobial agents were>70%.The infected patients were almost aged,with many underlying diseases,with long hospitalization time and various invasive treat ment,as well as receiving at least 2 kinds of antimicrobial agents before developing infection;some patients complicated with infections caused by the other pathogens,most were Pseudomonas aeruginosa(34.55%)and Stenotrophomonas maltophilia(20.00%)infections.Conclusion Patients with A.baumannii infections are in serious condition, antimicrobial resistance is high,realization of the clinical characteristics,infection distribution and drug resistance pattern are important to prevent and treat infections

  • 【文献出处】 中国感染控制杂志 ,Chinese Journal of Infection Control , 编辑部邮箱 ,2010年02期
  • 【分类号】R563.1
  • 【被引频次】7
  • 【下载频次】17
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