【摘要】 目的探讨肿瘤坏死因子TNFα-308G/A和TNFβG252A基因多态性与子宫内膜异位症的关系。方法运用多聚酶链反应技术检测100例子宫内膜异位症及100例正常人肿瘤坏死因子TNFα-308G/A和TNFβG252A基因多态性。结果TNFα-308G/A和TNFβG252A各种基因型频率在患者组与正常对照组之间的差异无统计学意义(P>0.05)。结论肿瘤坏死因子TNFα-308G/A和TNFβG252A基因多态性与子宫内膜异位症无明显相关。更多还原

【Abstract】 Objective To investigate the relationship between tumor necrosis factor(TNF) polymorphism and endometriosis’s disease.Methods The polymorphism of TNFα-308G / A and TNFβG252A was screened by PCR-RELP.Results There were no significant differences in the frequencies of TNFα-308G / A and TNFβG252A gene between the patients and control group(P> 0.05).Conclusion No evident association is found between TNFα-308G / A,TNFβG252A polymorphism and endometriosis.更多还原