【摘要】 目的:探讨白血病并发侵袭性肺曲霉菌(IPA)感染的X线及CT表现特征,提高对该病的认识。方法:回顾性分析经病原学及病理组织学证实为IPA的52例白血病患者的临床及影像资料,全部病例均常规做胸部X线及MSCT检查,其中48例做了2次以上的X线及CT复查。结果:本组IPA病灶形态多样化,表现为多发斑片及片状影12例,单发或多发小结节状影18例,出现"晕环"征14例,肺内肿块影9例,胸膜下楔型实变影5例,曲菌球及空气新月征8例,同时存在两种或两种以上表现39例,X线胸片和CT的病灶检出率分别为88.5%及100%。结论:IPA是白血病患者最常见并发症,早期出现的"晕环"征及中晚期出现的"空气新月征"较具特征性,对诊断有重要的参考价值,需密切结合临床及实验室检查。更多还原

【Abstract】 Objective:To study the X-ray and CT findings of invasive pulmonary aspergillosis (IPA) complicated with leukemia and to improve the understanding of this disease.Methods:Clinical and imaging data of IPA confirmed by etiology or histopathology were retrospectively analyzed in 52 cases with leukemia.All patients underwent conventional chest X-ray and MSCT examinations,48 of them underwent more than twice X-ray or CT follow-up.Results:The imaging findings were diverse on chest X-ray and CT:intrapulmonary multiple mottling shadows and patchy shadows were found in 12 cases,nodule or multinodules in 18 cases (halo sign in 14),mass shadow in 9 cases,subpleural wedge-shaped consolidation was seen in 5 cases,aspergillums balls and air crescent sign in 8 cases,and there were two or more imaging findings in 39 cases.Lesion detective rates of X-ray and CT were 88.5% and 100%.Conclusion:IPA is the most common complication with leukemia,its early and late imaging characteristics include halo sign and air crescent sign,which are of important reference value to the diagnosis of this disease if closely combined with clinical data and laboratory tests.更多还原