【摘要】 目的:研究非小细胞肺癌患者血清CYFRA21-1浓度与病理分期的关系。方法:应用放射免疫分析224例非小细胞肺癌患者血清CYFRA21-1的浓度,统计分析其与术后病理T、N分期的关系。结果:非小细胞肺癌患者血清CYFRA21-1浓度与T分期(T1vsT2,T1vsT3,P<0.05)及淋巴结转移(pN0vspN1,pN0vspN2,pN1vspN2,P<0.05)有显著统计学差异。结论:术前检测非小细胞肺癌患者血清CYFRA21-1浓度对判断T、N分期有重要的临床意义。更多还原

【Abstract】 Objective To study the relationship between of serum concentrations of CYFRA21-1 and to pathological staging in patients with non-small cell lung cancer.Methods Serum concentrations of CYFRA21-1 were determined with IRMA in 224 patients with non-small cell lung cancer.Results The serum CYFRA21-1 levels in patients with non-small cell lung carcinoma increased gradually as the tumor size enlarged.Levels in patients of T2 and T3 stages were significantly higher than those in patients of T1 stage,but the difference between those in patients of T2 stage and T3 stage were not significant.The serum CYFRA21-1 levels also incroased as the number of lymph nodes with metastasis increased.Differences of serum levels of CYFRA21-1 in patients of consecutive lymph node stages were all significant.Conclusion Preoperative detection of the serum concentration of CYFRA21-1 in patient with non-small cell lung cancer has important clinical significance on the judgement of T,N stages.更多还原