【摘要】 目的:探讨腹腔镜脾切除术治疗血液系统疾病的可行性及效果。方法:应用腹腔镜脾切除术治疗经内科治疗无效或治疗后复发的原发性血小板减少性紫癜(idiopathic thrombocytopenic purpura,ITP)患者42例,遗传性球形红细胞增多症(hereditary spherocytosis,HS)患者9例。结果:本组51例无手术死亡及严重并发症发生,脾切除术后血液检测指标均明显改善,术后第7天ITP患者的血小板计数均值由23×109/L升为618×109/L;HS患者的网织红细胞均值由18%降至2.1%,血红蛋白均值由6.1g/L升至9.8g/L。结论:腹腔镜脾切除对部分血液系统疾病的治疗具有微创、安全、有效、美容效果好、术后患者康复快等优点,值得推广应用。更多还原

【Abstract】 Objective:The purpose of the present study was to evaluate the feasibility and the effect of the treatment of hematopathy by laparoscopic splenectomy.Methods:Forty-two cases of idiopathic thrombocytopenic purpura(ITP) and 9 cases of hereditary spherocytosis(HS) who showed no effect or recurred after medical therapy were treated by laparoscopic splenectomy.Results:No mortality or serious complications occurred in all 51 cases.All of the blood indexes improved obviously after splenectomy.The average platelet count of ITP increased from 23×109/L to 618×109/L.Reticulocyte count of HS decreased from 18% to 2.1%.And,hemoglobin increased from 6.1g/L to 9.8g/L on the 7th day after splenectomy.No recurrence was found during the follow-up from 0.5 to 13 years.Conclusions:Laparoscopic splenectomy has advantages of mini-invasion,safety,utility,satisfied cosmesis and quick recovery in the treatment of some hematopathy,and is worthy of generalization and application.更多还原