【摘要】 目的探讨硝酸甘油联合小剂量多巴胺治疗肺心病心力衰竭的临床应用价值。方法对我院呼吸内科与老年病学科2004年1月至2006年12月收治的92例慢性阻塞性肺疾病急性加重期(AECOPD)肺心病失代偿期住院患者,随机分为治疗组和对照组,每组46例。对照组采用常规治疗,治疗组采用在常规治疗加用硝酸甘油和小剂量的多巴胺。观察两组的咳嗽、气喘、发绀、肺部啰音、双下肢水肿等症状及体征改善情况和平均住院天数、治愈率。结果治疗组临床症状及体征改善情况明显优于对照组,有显著性差异(P<0.05);平均住院天数治疗组比对照组减少;治疗组显效率71.74%,对照组显效率43.48%,有显著性差异(P<0.05)。结论硝酸甘油联合小剂量多巴胺治疗慢性肺心病心力衰竭疗效显著,值得临床推广。更多还原

【Abstract】 Objective To explore the clinical efficacy of using glyceryltrinitrate combined with low-dose dopamine to treat chronic cor pulmonale with cardia failure.Methods 98 cases of chronic cor pulmonale with AECOPD from January 2004 to December 2006 in Departments of Respiratory and Geriatric Medicine of our hospital were randomly divided into two groups.46 cases in the treatment group were treated with the conventional therapy plus glyceryltrinitrate and low-dose dopamine,while the conventional therapy was applied to 46 cases in the control group.Observation and comparison were made on their symptoms and signs of improvement(cough,asthma,hair clamp,pulmonary rales,edema of lower extremities),average hospitalization days and cure rates in the two groups.Results The treatment group had better clinical symptoms and signs than those in the control group with significant difference(P<0.05),and fewer hospital days in the treatment group.Compared with the significant efficiency 43.48% in the control group,the significant efficiency was 71.74% in the treatment group,which was significant difference(P<0.05).Conclusion Glyceryltrinitrate combined with low-dose dopamine have a great curative effect on chronic cor pulmonale with cardia failure,thus it is worthy of pupularization.更多还原