【摘要】 【目的】研究早期综合干预对早产低体重儿生后早期追赶生长及胰岛素敏感性的影响,以提高早产儿健康水平。【方法】将2008年1月—2009年2月在本院新生儿科住院的早产儿作为研究对象,按家长是否同意接受早期综合干预分为早期干预组和对照组。早期干预组:1)家长或抚养人参加科学育儿学习班;2)每天给婴儿做抚触、被动操、洗澡、游泳、晒太阳,尽可能与婴儿视觉交流、语言交流、提供适当的玩具等。对照组:不接受婴儿抚触等早期干预措施,常规育儿。两组婴儿满3个月时来院查体,查体内容包括:1)家长填写育儿问卷;2)测量婴儿体重、身长、头围;3)化验血常规、血胰岛素、血糖。用内稳态模式评估公式(HOMA)评价胰岛素敏感性。【结果】1)3个月时干预组体重、身长、头围的变化值(△SDS)与对照组比较差异有高度统计学意义(P<0.01);2)3个月时干预组血胰岛素敏感性较对照组明显增高(P<0.01)。【结论】早期综合干预能促进早产儿胃肠功能发育,提高早产儿血胰岛素敏感性,促进早产儿生后早期追赶生长。更多还原

【Abstract】 【Objective】Study the effects of early intervention on early catch-up growth and insulin sensitivity of preterm low weight infants in order to develop there health. 【Methods】105 preterm low weight infants were divided into intervention group(55 cases) and control group(50 cases).Early intervention group:they were given scientific care of,early education,touching,passive excise,bathing,swimming,sun-bashing,as possible given visual exchange,language exchange,provided toys,et al.Control group: weren’t given early intervention,only given route care infant.Two groups infants were given examination when they were three months.Including there parents’ questionnaire interview,infants’ weight,hight and head circumference,blood routine,serum insulin and serum glucose were measured.Insulin sensitivity was assessed with HOMA. 【Results】The △SDS of weigh,hight,and head circumference in intervention groups in 3 months were higher than those of the control group(P<0.01).The serum insulin sensitivity of the intervention group was much higher than that of the control group(P<0.01). 【Conclusions】Early intervention can improve serum insulin sensitivity of preterm and promote their early catch-up growth.更多还原